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NAD+

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For laboratory research use only. Not for human or veterinary use.

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is an endogenous coenzyme involved in cellular redox reactions and serves as a substrate for sirtuins, PARPs, and CD38. Research examines age-associated changes in NAD+ availability and their relationships with mitochondrial bioenergetics, DNA-repair activity, cellular stress responses, and sirtuin-dependent signaling pathways. For laboratory research use only.

Research focus

  • Longevity Research: NAD+ is investigated as a substrate for sirtuin- and PARP-associated pathways in experimental aging models. Research examines age-related changes in NAD+ availability and their relationships with sirtuin activity, genome maintenance, cellular senescence, and metabolic regulation. Buffered formulations are evaluated for physicochemical stability, pH control, and tissue-response characteristics.
  • Neuroscience Research: NAD+ is studied for its role in neuronal stress-response and survival pathways. Research examines SIRT1-associated signaling, PARP-1-dependent DNA repair, mitochondrial bioenergetics, oxidative-stress regulation, and age-related molecular changes in neural tissue.
  • Mitochondrial-Biology Research: NAD+ is evaluated as a redox cofactor involved in cellular respiration and metabolic electron transfer. Investigations focus on NAD+/NADH ratios, respiratory-complex activity, oxidative phosphorylation, mitochondrial membrane potential, and bioenergetic responses in models of mitochondrial dysfunction.
  • DNA-Repair Research: NAD+ is studied as a substrate for poly(ADP-ribose) polymerases. Research examines how changes in NAD+ availability influence PARP activity, DNA-damage responses, chromatin regulation, genomic stability, and cellular stress signaling.
  • Metabolic Research: NAD+ is investigated for its central role in cellular energy metabolism. Research endpoints include glycolysis, the tricarboxylic-acid cycle, fatty-acid oxidation, insulin-signaling pathways, substrate utilization, and metabolic adaptation.

Research Calculation Guide

Strength Total NAD+ per vial Vial size
500 mg 500 mg 3 mL
1000 mg 1000 mg 3 mL
For research reference only. Not intended for human dosing guidance.

Certificate of Analysis

Tested for potency, purity, and identity verification. COA generated for the current production batch.

Batch: Latest Available
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Quality Tested

Passed

Potency Review

Quantified to verify concentration within accepted labeled specification.

Passed

Purity Review

Assessed for peptide purity and absence of significant impurities by analytical methods.

Passed

Identity Verification

Confirmed by analytical testing to match reference peptide characteristics.

Passed

Batch Documentation

Batch records and test data maintained for traceability and transparency.

Frequently Asked Questions

Storage Conditions

Unreconstituted

Store at -20°C to 4°C (freezer or refrigerator). Stable for 24+ months.

Reconstituted

Refrigerate at 2–8°C. Use within 30 days for optimal stability.

Avoid

Repeated freeze-thaw cycles, direct sunlight, and temperatures above 25°C.

Safety & Compliance
  • Wear nitrile gloves and safety goggles when handling research compounds.
  • Work in a clean, controlled environment (laminar flow hood recommended).
  • Dispose of sharps and used materials in approved biohazard containers.
  • This product is for laboratory research use only (RUO) — not for human or veterinary use.
What is the difference between the 500 mg and 1000 mg options?

The total NAD+ content per vial differs. The compound is the same.

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